Bisphenol A

Bisphenol A, commonly abbreviated as BPA, is an organic compound with two phenol functional groups used to make polycarbonate plastic and epoxy resins, along with other applications.

Health effects

Bisphenol A is an endocrine disruptor, which can mimic the body's own hormones and may lead to negative health effects.

- perinatal BPA exposure acts to exert persistent effects on body weight and adiposity

- BPA's effects on fetal and infant brain development and behavior

-  potentiate the central dopaminergic systems, resulting in the supersensitivity to the drugs-of-abuse-induced reward effects and hyperlocomotion

- adverse effects on thyroid hormone action

- alters breast development and increases breast cancer risk

- growth of neuroblastoma cells

- permanently increase in prostate size

- increased prostate cancer

- leads to permanent DNA alterations in sensitivity to estrogen

-  adult male sexual dysfunction

- heart disease

- diabetes

- abnormally high levels of certain liver enzymes

- externalizing behaviors in two-year old children